Adverse effects caused by many drugs are comparable in animals and humans due to their similarities in genetics, anatomy, and physiology. Whilst the predictive value of animal studies is not perfect, it is likely to be far better than estimated since many new drugs stopped at the pre-clinical stage due to safety concerns never going …
Every year, millions of people benefit from medicines developed and tested in animals. Despite good progress in non-animal alternatives over recent years, animal research remains essential to drug discovery and development. Animal models of disease are used to test the efficacy of new medicines during the early discovery phase, and animals are used to assess …
Animal Welfare – Vivonics Replacement, Reduction, Refinement Policy Read More »
Recordings of arterial blood pressure from conscious, freely-moving animals can be made via telemetry devices and are used routinely during the drug discovery and development process to assess the cardiovascular safety of new drug molecules before they are tested in human trials. Fully implantable telemetry devices sample the blood pressure waveform 500 to 1000 times …
Waveform analysis of blood pressure telemetry data Read More »
Animal models are used in the discovery of new drugs and vaccines used to treat human diseases. In addition to helping test drug efficacy, studies in laboratory animals are also used to help determine what unwanted effects the drug may have. These safety studies enable developers to deselect candidate molecules with associated hazards and ensure …
Why is the rat telemetry assay a useful tool in safety pharmacology studies? Read More »
What is telemetry? Telemetry is the science or process of making measurements from objects at a distance via transmission of information back to receiving equipment. It is derived from the Greek words ‘tele’, meaning remote, and ‘metron’, meaning measure. Telemetry is used across a wide range of industries, including space science, agriculture, motor racing, meteorology …
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