{"id":2108,"date":"2022-09-07T11:27:27","date_gmt":"2022-09-07T10:27:27","guid":{"rendered":"https:\/\/vivonics-preclinical.com\/?p=2108"},"modified":"2023-02-23T12:44:09","modified_gmt":"2023-02-23T12:44:09","slug":"animal-welfare-vivonics-replacement-reduction-refinement-policy","status":"publish","type":"post","link":"https:\/\/vivonics-preclinical.com\/2022\/09\/07\/animal-welfare-vivonics-replacement-reduction-refinement-policy\/","title":{"rendered":"Animal Welfare &#8211; Vivonics Replacement, Reduction, Refinement Policy"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2108\" class=\"elementor elementor-2108\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"has_ae_slider elementor-section elementor-top-section elementor-element elementor-element-3b5dabd elementor-section-boxed elementor-section-height-default elementor-section-height-default ae-bg-gallery-type-default\" data-id=\"3b5dabd\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ae_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5c6aa7c5 ae-bg-gallery-type-default\" data-id=\"5c6aa7c5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3c04c08e elementor-widget elementor-widget-text-editor\" data-id=\"3c04c08e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 25-04-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Every year, millions of people benefit from medicines developed and tested in animals.<\/p><p>Despite good progress in non-animal alternatives over recent years, animal research remains essential to drug discovery and development. Animal models of disease are used to test the efficacy of new medicines during the early discovery phase, and animals are used to assess the safety of new medicines at a later stage before testing in human clinical trials.<\/p><p>Vivonics conducts animal research on behalf of customers who develop new therapeutics for humans.<\/p><p>Our work is conducted per the <a href=\"https:\/\/www.legislation.gov.uk\/ukpga\/1986\/14\/contents\">UK Animals (Scientific Procedures) Act\u00a01986\u00a0<\/a>under an authorised project licence. The welfare of the animals is of the utmost importance to Vivonics and central to good quality robust science. Animals are treated with care and compassion, and we are committed to the continual application of the principles of the 3Rs (replacement, reduction, and refinement) during our research.<\/p><h5><strong>Replacement:<\/strong><\/h5><p>Before embarking on a study, we check that animals are needed to achieve the scientific objective of our customers.\u00a0Where non-animal alternatives exist (e.g. in silico or in vitro assays), we can advise on assay methods and potential suppliers.<\/p><h5><strong>Reduction:<\/strong><\/h5><p>We involve our\u00a0<a href=\"https:\/\/vivonics-preclinical.com\/consultancy\/\">statistical partner\u00a0<\/a>throughout the process to ensure animal studies are appropriately designed using the minimum number of animals possible and analysed to yield precise, interpretable data that will be valuable to our customers.<\/p><h5><strong>Refinement:<\/strong><\/h5><p>At Vivonics, we strive to use the most refined in vivo methods to enhance the welfare of the animals in our care and improve the quality of our data. We follow the<strong>\u00a0<\/strong><a href=\"https:\/\/www.gov.uk\/government\/publications\/code-of-practice-for-the-housing-and-care-of-animals-bred-supplied-or-used-for-scientific-purposes\">Code of Practice for the Housing and Care of Animals used in Scientific Procedures\u00a0<\/a>but aim for even higher standards. We group-house animals in\u00a0<a href=\"https:\/\/vivonics-preclinical.com\/telemetry\/\">telemetry studies<\/a>, use large double-decker cages and provide regular access to even larger socialisation and play cages. The most refined dosing and sampling techniques are also employed to minimise animal discomfort.<\/p><p>Our trained animal technicians keep up to date with advances in animal science through organisations such as the\u00a0<a href=\"https:\/\/www.nc3rs.org.uk\/\">UK NC3Rs\u00a0<\/a>and implement new practices that positively impact animal welfare. They are also encouraged to improve our procedures and keep animal welfare a top priority.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_ae_slider elementor-section elementor-top-section elementor-element elementor-element-9e48bd5 elementor-section-boxed elementor-section-height-default elementor-section-height-default ae-bg-gallery-type-default\" data-id=\"9e48bd5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ae_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-333adf3 ae-bg-gallery-type-default\" data-id=\"333adf3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ac5c484 elementor-author-box--avatar-yes elementor-author-box--biography-yes elementor-author-box--link-no elementor-widget elementor-widget-author-box\" data-id=\"ac5c484\" data-element_type=\"widget\" data-widget_type=\"author-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/vivonics-preclinical.com\/wp-content\/plugins\/elementor-pro\/assets\/css\/widget-theme-elements.min.css\">\t\t<div class=\"elementor-author-box\">\n\t\t\t\t\t\t\t<div  class=\"elementor-author-box__avatar\">\n\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/secure.gravatar.com\/avatar\/01f20fdf0e109b40f64c8a16186dc4f6?s=300&#038;d=mm&#038;r=g\" alt=\"Picture of Vivonics\" loading=\"lazy\">\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"elementor-author-box__text\">\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-author-box__bio\">\n\t\t\t\t\t\tMatt is a highly trained scientist with many years of experience working in drug discovery and safety pharmacology groups in large pharmaceutical companies and CROs.\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Every year, millions of people benefit from medicines developed and tested in animals. Despite good progress in non-animal alternatives over recent years, animal research remains essential to drug discovery and development. Animal models of disease are used to test the efficacy of new medicines during the early discovery phase, and animals are used to assess [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":2110,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[10],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Animal Welfare - Vivonics Replacement, Reduction, Refinement Policy<\/title>\n<meta name=\"description\" content=\"Vivonics replacement, reduction and refinement policy is aimed at keeping animal welfare a top priority &amp; 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